HEMTAC WEE1 degrader-1, CAS [[3002417-64-0]] Preis auf Anfrage

Produktübersicht

• Artikelname: HEMTAC WEE1 degrader-1, CAS [[3002417-64-0]] Preis auf Anfrage
• Artikelnummer: MCE-HY-173320
• Hersteller Artikelnummer: HY-173320
• Alternativnummer: MCE-HY-173320-1MG,MCE-HY-173320-10MG,MCE-HY-173320-5MG,MCE-HY-173320-25MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

HEMTAC WEE1 degrader-1 is a HSP90-mediated targeting chimera (HEMTAC) degrader of WEE1 (HSP90 enzyme inhibitory activity is IC50: 16.76 nM). HEMTAC WEE1 degrader-1 promotes the ubiquitination and degradation of WEE1. HEMTAC WEE1 degrader-1 blocks the G2/M cell cycle. HEMTAC WEE1 degrader-1 has anticancer activity in acute myeloid leukemia (AML) patient-derived xenograft (PDX) models. HEMTAC WEE1 degrader-1 can be used in AML research. (Pink: HSP90 binder, Blue: WEE1 ligand, Black: linker)[1].

Produkteigenschaften

• Molekulargewicht: 1062.27
• Reinheit: 99.7800
• CAS Nummer: [3002417-64-0]
• Formel: C57H71N15O6
• Target-Kategorie: HSP,Wee1

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound