HEMTAC WEE1 degrader-1, CAS [[3002417-64-0]] Preis auf Anfrage

Product Overview

• Article Name: HEMTAC WEE1 degrader-1, CAS [[3002417-64-0]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-173320
• Supplier Catalog Number: HY-173320
• Alternative Catalog Number: MCE-HY-173320-1MG,MCE-HY-173320-10MG,MCE-HY-173320-5MG,MCE-HY-173320-25MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

HEMTAC WEE1 degrader-1 is a HSP90-mediated targeting chimera (HEMTAC) degrader of WEE1 (HSP90 enzyme inhibitory activity is IC50: 16.76 nM). HEMTAC WEE1 degrader-1 promotes the ubiquitination and degradation of WEE1. HEMTAC WEE1 degrader-1 blocks the G2/M cell cycle. HEMTAC WEE1 degrader-1 has anticancer activity in acute myeloid leukemia (AML) patient-derived xenograft (PDX) models. HEMTAC WEE1 degrader-1 can be used in AML research. (Pink: HSP90 binder, Blue: WEE1 ligand, Black: linker)[1].

Product Properties

• Molecular Weight: 1062.27
• Purity: 99.7800
• CAS Number: [3002417-64-0]
• Formula: C57H71N15O6
• Target: HSP,Wee1

Application Notes

• Application Notes: MCE Product type: Reference compound