beta-Glucuronidase-IN-3, CAS [[3081681-34-4]] Preis auf Anfrage
Artikelnummer:
MCE-HY-173397
Hersteller Artikelnummer:
HY-173397
Alternativnummer:
MCE-HY-173397-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
beta-Glucuronidase-IN-3 (Compound 49) is a covalent allosteric beta-glucuronidase inhibitor. beta-Glucuronidase-IN-3 has potent inhibitory activity against Escherichia coli beta-glucuronidase (EcGUS) (IC50: 12.9 nM). beta-Glucuronidase-IN-3 exerts its inhibitory effect by reversibly covalently modifying the cysteine residues (Cys28, Cys443, and Cys197) of EcGUS. beta-Glucuronidase-IN-3 can be used in the study of intestinal microbiota-related diseases, especially to alleviate the toxic side effects of Irinotecan (HY-16562) and nonsteroidal anti-inflammatory drugs (NSAIDs)[1].
Molekulargewicht:
264.14
CAS Nummer:
[3081681-34-4]
Formel:
C10H7N3OSe
Target-Kategorie:
Bacterial,beta-glucuronidase
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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