beta-Glucuronidase-IN-3, CAS [[3081681-34-4]] Preis auf Anfrage

Product Overview

• Article Name: beta-Glucuronidase-IN-3, CAS [[3081681-34-4]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-173397
• Supplier Catalog Number: HY-173397
• Alternative Catalog Number: MCE-HY-173397-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

beta-Glucuronidase-IN-3 (Compound 49) is a covalent allosteric beta-glucuronidase inhibitor. beta-Glucuronidase-IN-3 has potent inhibitory activity against Escherichia coli beta-glucuronidase (EcGUS) (IC50: 12.9 nM). beta-Glucuronidase-IN-3 exerts its inhibitory effect by reversibly covalently modifying the cysteine residues (Cys28, Cys443, and Cys197) of EcGUS. beta-Glucuronidase-IN-3 can be used in the study of intestinal microbiota-related diseases, especially to alleviate the toxic side effects of Irinotecan (HY-16562) and nonsteroidal anti-inflammatory drugs (NSAIDs)[1].

Product Properties

• Molecular Weight: 264.14
• CAS Number: [3081681-34-4]
• Formula: C10H7N3OSe
• Target: Bacterial,beta-glucuronidase

Application Notes

• Application Notes: MCE Product type: Reference compound1