Dimethyl fumarate (DMF) is an orally active and brain-penetrant Nrf2 activator and induces upregulation of antioxidant gene expression. Dimethyl fumarate induces necroptosis in colon cancer cells through GSH depletion/ROS increase/MAPKs activation pathway, and also induces cell autophagy. Dimethyl fumarate can be used for multiple sclerosis research[1][2].
Molekulargewicht:
144.13
Reinheit:
99.99
CAS Nummer:
[624-49-7]
Formel:
C6H8O4
Target-Kategorie:
Autophagy,Endogenous Metabolite,HIV,Keap1-Nrf2,Reactive Oxygen Species (ROS)
Anwendungsbeschreibung:
MCE Product type: Natural Products
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