Dimethyl fumarate (DMF) is an orally active and brain-penetrant Nrf2 activator and induces upregulation of antioxidant gene expression. Dimethyl fumarate induces necroptosis in colon cancer cells through GSH depletion/ROS increase/MAPKs activation pathway, and also induces cell autophagy. Dimethyl fumarate can be used for multiple sclerosis research[1][2].
Molecular Weight:
144.13
Purity:
99.99
CAS Number:
[624-49-7]
Formula:
C6H8O4
Target:
Autophagy,Endogenous Metabolite,HIV,Keap1-Nrf2,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Natural Products
* VAT and and shipping costs not included. Errors and price changes excepted
