Rofecoxib-d5 is the deuterium labeled Rofecoxib. Rofecoxib is a potent, specific and orally active COX-2 inhibitor, with IC50s of 26 and 18 nM for human COX-2 in human osteosarcoma cells and Chinese hamster ovary cells, with a 1000-fold selectivity for COX-2 over human COX-1 (IC50 > 50 µM in U937 cells and > 15 µM in Chinese hamster ovary cells)[1][2].
Molekulargewicht:
319.39
CAS Nummer:
[544684-93-7]
Formel:
C17H9D5O4S
Target-Kategorie:
COX,Isotope-Labeled Compounds
Anwendungsbeschreibung:
MCE Product type: Isotope-Labeled Compounds
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
