Rofecoxib-d5 is the deuterium labeled Rofecoxib. Rofecoxib is a potent, specific and orally active COX-2 inhibitor, with IC50s of 26 and 18 nM for human COX-2 in human osteosarcoma cells and Chinese hamster ovary cells, with a 1000-fold selectivity for COX-2 over human COX-1 (IC50 > 50 µM in U937 cells and > 15 µM in Chinese hamster ovary cells)[1][2].
Molecular Weight:
319.39
CAS Number:
[544684-93-7]
Formula:
C17H9D5O4S
Target:
COX,Isotope-Labeled Compounds
Application Notes:
MCE Product type: Isotope-Labeled Compounds
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