()-Huperzine A, an active Lycopodium alkaloid extracted from traditional Chinese herb, is a potent, selective and reversible acetylcholinesterase (AChE) inhibitor and has been widely used in China for the treatment of Alzheimers disease (AD). IC50 value: Target: AChE ()-Huperzine A exhibited protective effects against d-gal-induced hepatotoxicity and inflamm-aging by inhibiting AChE activity and via the activation of the cholinergic anti-inflammatory pathway. The ()-Huperzine A mechanism might be involved in the inhibition of DAMPs-mediated NF-kappaB nuclear localization and activation. ()-Huperzine A is a potential therapeutic agent for Alzheimers disease.
Molekulargewicht:
242.32
Reinheit:
98.73
CAS Nummer:
[120786-18-7]
Formel:
C15H18N2O
Target-Kategorie:
Cholinesterase (ChE)
Anwendungsbeschreibung:
MCE Product type: Natural Products
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