()-Huperzine A is the racemate of (-)-Huperzine A (HY-17387). (-)-Huperzine A is an alkaloid isolated from Huperzia serrata, with neuroprotective activity. (-)-Huperzine A is a potent, highly specific, reversible and blood-brain barrier penetrant inhibitor of acetylcholinesterase (AChE), with an IC50 of 82 nM. (-)-Huperzine A also is non-competitive antagonist of N-methyl-D-aspartate glutamate (NMDA) receptor. (-)-Huperzine A is developed for the research of neurodegenerative diseases, including Alzheimers disease[1][2][3][4][5].
Molecular Weight:
242.32
Purity:
98.73
CAS Number:
[120786-18-7]
Formula:
C15H18N2O
Target:
Cholinesterase (ChE),Drug Isomer,iGluR
Application Notes:
MCE Product type: Natural Products
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