EXO1-IN-1, CAS [[1111188-09-0]] Preis auf Anfrage

Produktübersicht

• Artikelname: EXO1-IN-1, CAS [[1111188-09-0]] Preis auf Anfrage
• Artikelnummer: MCE-HY-174143
• Hersteller Artikelnummer: HY-174143
• Alternativnummer: MCE-HY-174143-5MG, MCE-HY-174143-10MG, MCE-HY-174143-25MG, MCE-HY-174143-50MG, MCE-HY-174143-100MG, MCE-HY-174143-1MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

EXO1-IN-1 (Compound F684) is a potent and selective inhibitor of exonuclease 1 (EXO1) (IC50= 15.7 µM). EXO1-IN-1 suppresses DNA end resection, promotes the accumulation of DNA double-strand breaks, and triggers S-phase PARylation, disrupts DNA repair pathways in homologous recombination-deficient (HRD) cancer cells, and selectively kills tumor cells with defects in HR genes like BRCA1/2. EXO1-IN-1 is promising for research of homologous recombination-deficient cancer (such as BRCA-related tumors)[1].

Produkteigenschaften

• Molekulargewicht: 465.56
• CAS Nummer: [1111188-09-0]
• Formel: C25H27N3O4S
• Target-Kategorie: Others

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound1