HSV-1/HSV-2-IN-3, CAS [[3016396-78-1]] Preis auf Anfrage

Produktübersicht

• Artikelname: HSV-1/HSV-2-IN-3, CAS [[3016396-78-1]] Preis auf Anfrage
• Artikelnummer: MCE-HY-174252
• Hersteller Artikelnummer: HY-174252
• Alternativnummer: MCE-HY-174252-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

HSV-1/HSV-2-IN-3 inhibits the herpes-simplex-virus (HSV) helicase-primase complex, blocking the coordinated DNA-unwinding and primer-synthesis steps required for viral genome replication. HSV-1/HSV-2-IN-3 exhibits an EC50 of 7.0 nM against HSV-2 in a gD-immunofluorescence cell assay containing 2 % FBS and 57.5 nM when 10 % human serum is present. HSV-1/HSV-2-IN-3 achieves an EC50 of 1.1 nM in a qPCR replication assay. HSV-1/HSV-2-IN-3 shows strong selectivity over human carbonic-anhydrase off-targets (IC50 ~ 2.9 µM for hCA II and > 35 µM for hCA I). HSV-1/HSV-2-IN-3 can be studied in anti-HSV research[1].

Produkteigenschaften

• Molekulargewicht: 451.51
• CAS Nummer: [3016396-78-1]
• Formel: C24H22FN3O3S
• Target-Kategorie: HSV

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound