HSV-1/HSV-2-IN-3, CAS [[3016396-78-1]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-174252
Supplier Catalog Number:
HY-174252
Alternative Catalog Number:
MCE-HY-174252-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
HSV-1/HSV-2-IN-3 inhibits the herpes-simplex-virus (HSV) helicase-primase complex, blocking the coordinated DNA-unwinding and primer-synthesis steps required for viral genome replication. HSV-1/HSV-2-IN-3 exhibits an EC50 of 7.0 nM against HSV-2 in a gD-immunofluorescence cell assay containing 2 % FBS and 57.5 nM when 10 % human serum is present. HSV-1/HSV-2-IN-3 achieves an EC50 of 1.1 nM in a qPCR replication assay. HSV-1/HSV-2-IN-3 shows strong selectivity over human carbonic-anhydrase off-targets (IC50 ~ 2.9 µM for hCA II and > 35 µM for hCA I). HSV-1/HSV-2-IN-3 can be studied in anti-HSV research[1].
Molecular Weight:
451.51
CAS Number:
[3016396-78-1]
Formula:
C24H22FN3O3S
Target:
HSV
Application Notes:
MCE Product type: Reference compound
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