GSK-3beta inhibitor 27 (Compound 1c) is a reversible and competitive GSK-3beta inhibitor with an IC50 value of 2.2 µM. GSK-3beta inhibitor 27 inhibits tau hyperphosphorylation, reduces Abeta protein aggregation and possesses metal chelation and neuroprotective potential. GSK-3beta inhibitor 27 is promising for research of neurodegenerative diseases (such as Alzheimers disease)[1].
Molekulargewicht:
332.78
Formel:
C16H17ClN4O2
Target-Kategorie:
Amyloid-beta,GSK-3
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
