GSK-3beta inhibitor 27 (Compound 1c) is a reversible and competitive GSK-3beta inhibitor with an IC50 value of 2.2 µM. GSK-3beta inhibitor 27 inhibits tau hyperphosphorylation, reduces Abeta protein aggregation and possesses metal chelation and neuroprotective potential. GSK-3beta inhibitor 27 is promising for research of neurodegenerative diseases (such as Alzheimers disease)[1].
Molecular Weight:
332.78
Formula:
C16H17ClN4O2
Target:
Amyloid-beta,GSK-3
Application Notes:
MCE Product type: Reference compound
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