NU-PRO-1 is a covalent Telomerase reverse transcriptase (TERT) PROTAC degrader. NU-PRO-1 induces transient, VHL- and proteasome-dependent proteasomal degradation of TERT in cancer cells. NU-PRO-1 delays DNA repair in irradiated cancer cells without inducing DNA damage on its own. NU-PRO-1 can be used for the research of cancer[1].
Molekulargewicht:
1021.14
Formel:
C50H62F2N8O11S
Target-Kategorie:
PROTACs,Telomerase
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten