NU-PRO-1 is a covalent Telomerase reverse transcriptase (TERT) PROTAC degrader. NU-PRO-1 induces transient, VHL- and proteasome-dependent proteasomal degradation of TERT in cancer cells. NU-PRO-1 delays DNA repair in irradiated cancer cells without inducing DNA damage on its own. NU-PRO-1 can be used for the research of cancer[1].
Molecular Weight:
1021.14
Formula:
C50H62F2N8O11S
Target:
PROTACs,Telomerase
Application Notes:
MCE Product type: Reference compound
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