TREM2 agonist-4 is a TREM2 agonist with a Kd value of 12.7 µM. TREM2 agonist-4 stabilizes a transient binding pocket on TREM2 to drive downstream signaling. TREM2 agonist-4 increases Syk phosphorylation and enhances the phagocytic function of microglia. TREM2 agonist-4 can be used in the research of neurodegenerative diseases such as Alzheimers disease[1].
Molekulargewicht:
468.65
Reinheit:
99.81
Formel:
C27H36N2O3S
Target-Kategorie:
Syk,TREM receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
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