TREM2 agonist-4 (Compound 4a) is a TREM2 agonist with a Kd value of 45.9 µM. TREM2 agonist-4 can activate downstream signaling pathways of TREM2 and enhance the phagocytic function of microglia. TREM2 agonist-4 can be used in the research of neurodegenerative diseases such as Alzheimers disease[1].
Molecular Weight:
468.65
Formula:
C27H36N2O3S
Target:
TREM receptor
Application Notes:
MCE Product type: Reference compound
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