AR antagonist 15, CAS [[1790308-86-9]] Preis auf Anfrage
Artikelnummer:
MCE-HY-174391
Hersteller Artikelnummer:
HY-174391
Alternativnummer:
MCE-HY-174391-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
AR antagonist 15 is an orally active androgen receptor (AR) antagonist with the IC50 of 97 nM for ART787A. AR antagonist 15 disrupts AR nuclear translocation, hinders AR homodimerization, and suppresses transcription of AR-regulated genes by competitive binding to the ligand binding pocket. AR antagonist 15 can significantly lower the prostate-specific antigen (PSA) level. AR antagonist 15 induces apoptosis by reducing the expression of apoptosis pathway related proteins. AR antagonist 15 can be used for the research of prostate cancer[1].
Molekulargewicht:
346.44
CAS Nummer:
[1790308-86-9]
Formel:
C18H22N2O3S
Target-Kategorie:
Androgen Receptor,Apoptosis
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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