AR antagonist 15, CAS [[1790308-86-9]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-174391
Supplier Catalog Number:
HY-174391
Alternative Catalog Number:
MCE-HY-174391-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
AR antagonist 15 is an orally active androgen receptor (AR) antagonist with the IC50 of 97 nM for ART787A. AR antagonist 15 disrupts AR nuclear translocation, hinders AR homodimerization, and suppresses transcription of AR-regulated genes by competitive binding to the ligand binding pocket. AR antagonist 15 can significantly lower the prostate-specific antigen (PSA) level. AR antagonist 15 induces apoptosis by reducing the expression of apoptosis pathway related proteins. AR antagonist 15 can be used for the research of prostate cancer[1].
Molecular Weight:
346.44
CAS Number:
[1790308-86-9]
Formula:
C18H22N2O3S
Target:
Androgen Receptor,Apoptosis
Application Notes:
MCE Product type: Reference compound1
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