7,4-Dimethoxy-3-hydroxyflavone, CAS [[13198-99-7]] Preis auf Anfrage

Produktübersicht

• Artikelname: 7,4-Dimethoxy-3-hydroxyflavone, CAS [[13198-99-7]] Preis auf Anfrage
• Artikelnummer: MCE-HY-174829
• Hersteller Artikelnummer: HY-174829
• Alternativnummer: MCE-HY-174829-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

7,4-Dimethoxy-3-hydroxyflavone is an orally active PAR4 antagonist. 7,4-Dimethoxy-3-hydroxyflavone inhibits PAR4-mediated human platelet aggregation with an IC50 of 1.4 µM. 7,4-Dimethoxy-3-hydroxyflavone inhibits PAR4-mediated human platelet aggregation and PAR4 signaling pathways, including NF-kappaB, Ca2+/protein kinase C, Akt, ERK and p38. 7,4-Dimethoxy-3-hydroxyflavone prevents vascular PAR4 expression, endothelial dysfunction and ameliorates oxidative stress in Streptozotocin (STZ) (HY-13753)-induced diabetic mice. 7,4-Dimethoxy-3-hydroxyflavone prevents thrombosis in mice without affecting bleeding time[1][2].

Produkteigenschaften

• Molekulargewicht: 298.29
• CAS Nummer: [13198-99-7]
• Formel: C17H14O5
• Target-Kategorie: Akt,Calcium Channel,ERK,NF-kappaB,p38 MAPK,PKC,Protease Activated Receptor (PAR),Reactive Oxygen Species (ROS)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound1