AF151

Produktübersicht

• Artikelname: AF151
• Artikelnummer: MCE-HY-174873
• Hersteller Artikelnummer: HY-174873
• Alternativnummer: MCE-HY-174873-10MMX1ML,MCE-HY-174873-50MG,MCE-HY-174873-25MG,MCE-HY-174873-10MG,MCE-HY-174873-5MG,MCE-HY-174873-1MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

AF151 is a METTL3 PROTAC degrader with the DC50 of 0.43 µM in MOLM-13 cells. AF151 inhibits cell growth by significantly degrading METTL3 protein and reducing m6A levels. AF151 can induce cell apoptosis and reduce the level of Bcl-2 protein. AF151 can be used for research on cancer such as acute myeloid leukemia (AML). (Pink: METTL3 Ligand (HY-174874), Blue: VHL Ligand (HY-125845), Black: Linker, VHL Ligand+Linker (HY-174875))[1].

Produkteigenschaften

• Molekulargewicht: 1043.32
• Reinheit: 98.87
• Formel: C61H70N8O6S
• Target-Kategorie: Apoptosis,Bcl-2 Family,METTL3,PROTACs

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound1