VCP/p97 IN-3, CAS [[3098437-66-9]] Preis auf Anfrage

Produktübersicht

• Artikelname: VCP/p97 IN-3, CAS [[3098437-66-9]] Preis auf Anfrage
• Artikelnummer: MCE-HY-174984
• Hersteller Artikelnummer: HY-174984
• Alternativnummer: MCE-HY-174984-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

VCP/p97 IN-3 is a VCP/p97 allosteric inhibitor. VCP/p97 IN-3 shows the inhibitory activity against the VCP proteins with an IC50 of 9 nM and the mutant VCP proteins with IC50 of 12 nM (N660K) and 19 nM (V474A/D649A). VCP/p97 IN-3 increases K48-linked ubiquitination and the level of cleaved caspase-3. VCP/p97 IN-3 activates ER-stress and the UPR. VCP/p97 IN-3 inhibits tumor growth in RPMI-8226 cell subcutaneous xenograft mouse models. VCP/p97 IN-3 can be used for the study of multiple myeloma[1].

Produkteigenschaften

• Molekulargewicht: 606.69
• CAS Nummer: [3098437-66-9]
• Formel: C31H32F2N6O3S
• Target-Kategorie: Caspase,p62,p97

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound