EGFR-IN-12 (Standard), CAS [[879127-07-8]] Preis auf Anfrage
Artikelnummer:
MCE-HY-17499R
Hersteller Artikelnummer:
HY-17499R
Alternativnummer:
MCE-HY-17499R-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
EGFR-IN-12 (Standard) is the analytical standard of EGFR-IN-12. This product is intended for research and analytical applications. EGFR-IN-12 is a 4,6-disubstituted pyrimidine and is a potent, ATP-competitive, irreversible and highly selective EGFR inhibitor with an IC50of 21 nM. EGFR-IN-12 also inhibits mutant EGFRL858R and EGFRL861Q with IC50s of 63 nM and 4 nM, respectively. EGFR-IN-12 displays strong selectivity for EGFR over HER4 (IC50 = 7640 nM) and a panel of 55 other kinases. EGFR-IN-12 induces cells apoptosis and has antitumor activity[1][2].
Molekulargewicht:
413.40
CAS Nummer:
[879127-07-8]
Formel:
C21H18F3N5O
Target-Kategorie:
Apoptosis,EGFR,Reference Standards
Anwendungsbeschreibung:
MCE Product type: Reference Standards
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
