RIPK2-IN-8, CAS [[3036254-29-9]] Preis auf Anfrage
Artikelnummer:
MCE-HY-175026
Hersteller Artikelnummer:
HY-175026
Alternativnummer:
MCE-HY-175026-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
RIPK2-IN-8 is an orally active and highly selective RIPK2 inhibitor (IC50 = 11 nM). RIPK2-IN-8 is highly selective for RIPK2 over RIPK1 (IC50 > 30,000 nM) and has a moderate inhibitory effect on RIPK3 (IC50 = 44.61 nM). RIPK2-IN-8 inhibits the NOD2-RIPK2 signaling pathway and the expression of the inflammatory cytokines IL-6 and TNFalpha, thereby exerting anti-inflammatory effects. RIPK2-IN-8 has demonstrated anti-inflammatory and hepatoprotective effects in an acute liver injury (ALI) model and can be used in ALI research[1].
Molekulargewicht:
453.56
CAS Nummer:
[3036254-29-9]
Formel:
C22H20FN5OS2
Target-Kategorie:
Interleukin Related,NF-kappaB,p38 MAPK,RIP kinase
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
