10-Butyl Ether Minocycline, CAS [[488815-65-2]] Preis auf Anfrage
Artikelnummer:
MCE-HY-175275
Hersteller Artikelnummer:
HY-175275
Alternativnummer:
MCE-HY-175275-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Alternative Synonym:
BEM
10-Butyl Ether Minocycline (BEM), a Minocycline (HY-17412A) derivative, is an MMP-8 and MMP-9 inhibitor with IC50s of 69.4 µM and 47.0 µM, respectively. 10-Butyl Ether Minocycline suppresses LPS (HY-D1056)-induced microglial activation. 10-Butyl Ether Minocycline inhibits VEGF-induced endothelial cell migration and L-Glutamine (HY-N0390)-induced ROS levels. 10-Butyl Ether Minocycline significantly reduces alcohol consumption in the Chronic Intermittent Ethanol (CIE) mouse model of alcohol dependence. 10-Butyl Ether Minocycline can be used for the study of neuroimmune-inflammatory diseases and Alcohol use disorder (AUD)[1].
Molekulargewicht:
513.58
CAS Nummer:
[488815-65-2]
Formel:
C27H35N3O7
Target-Kategorie:
Lipoxygenase,MMP,Reactive Oxygen Species (ROS)
Anwendungsbeschreibung:
MCE Product type: Reference compound1
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten