10-Butyl Ether Minocycline, CAS [[488815-65-2]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-175275
Supplier Catalog Number:
HY-175275
Alternative Catalog Number:
MCE-HY-175275-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
BEM
10-Butyl Ether Minocycline (BEM), a Minocycline (HY-17412A) derivative, is an MMP-8 and MMP-9 inhibitor with IC50s of 69.4 µM and 47.0 µM, respectively. 10-Butyl Ether Minocycline suppresses LPS (HY-D1056)-induced microglial activation. 10-Butyl Ether Minocycline inhibits VEGF-induced endothelial cell migration and L-Glutamine (HY-N0390)-induced ROS levels. 10-Butyl Ether Minocycline significantly reduces alcohol consumption in the Chronic Intermittent Ethanol (CIE) mouse model of alcohol dependence. 10-Butyl Ether Minocycline can be used for the study of neuroimmune-inflammatory diseases and Alcohol use disorder (AUD)[1].
Molecular Weight:
513.58
CAS Number:
[488815-65-2]
Formula:
C27H35N3O7
Target:
Lipoxygenase,MMP,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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