PROTAC c-Met degrader-5 Preis auf Anfrage

Produktübersicht

• Artikelname: PROTAC c-Met degrader-5 Preis auf Anfrage
• Artikelnummer: MCE-HY-175320
• Hersteller Artikelnummer: HY-175320
• Alternativnummer: MCE-HY-175320-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

PROTAC c-Met degrader-5 (Compound D19) is an orally active c-Met PROTAC degrader with DC50s of 0.42 and 0.32 nM in EBC-1 and Hs746T cells, respectively. PROTAC c-Met degrader-5 significantly induces cell apoptosis, G1 cell cycle arrest, and inhibits cell migration and invasion. PROTAC c-Met degrader-5 has potent antiproliferative and degradation efficacy against c-Met-addicted cancer cells and Tepotinib (HY-14721)-resistant cancer cells[1]. Pink: c-Met ligand (HY-W425461), Blue: CRBN ligase ligand (HY-14658), Black: linker

Produkteigenschaften

• Molekulargewicht: 846.93
• Formel: C47H46N10O6
• Target-Kategorie: Apoptosis,c-Met/HGFR,PROTACs,STAT

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound