Enpp-1-IN-27, CAS [[3105103-33-8]] Preis auf Anfrage

Produktübersicht

• Artikelname: Enpp-1-IN-27, CAS [[3105103-33-8]] Preis auf Anfrage
• Artikelnummer: MCE-HY-175478
• Hersteller Artikelnummer: HY-175478
• Alternativnummer: MCE-HY-175478-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

Enpp-1-IN-27 is a selective ENPP1 inhibitor with an IC50 of 14.68 nM, exhibiting approximately 410-fold selectivity against ENPP2 and 10-fold selectivity against ENPP3. Enpp-1-IN-27 stabilizes cGAMP levels and activates the STING pathway, promoting cytokine release and enhancing innate immune responses. Enpp-1-IN-27 induces ISRE activation and amplified cGAMP-mediated immune responses and shows the desired antitumor efficacy in the 4T1 and CT26 syngeneic mouse models. Enpp-1-IN-27 can used for the studies of breast cancer and colon cancer[1].

Produkteigenschaften

• Molekulargewicht: 374.85
• CAS Nummer: [3105103-33-8]
• Formel: C13H19ClN6O3S
• Target-Kategorie: Phosphodiesterase (PDE),STING

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound