Enpp-1-IN-27, CAS [[3105103-33-8]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-175478
Supplier Catalog Number:
HY-175478
Alternative Catalog Number:
MCE-HY-175478-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Enpp-1-IN-27 is a selective ENPP1 inhibitor with an IC50 of 14.68 nM, exhibiting approximately 410-fold selectivity against ENPP2 and 10-fold selectivity against ENPP3. Enpp-1-IN-27 stabilizes cGAMP levels and activates the STING pathway, promoting cytokine release and enhancing innate immune responses. Enpp-1-IN-27 induces ISRE activation and amplified cGAMP-mediated immune responses and shows the desired antitumor efficacy in the 4T1 and CT26 syngeneic mouse models. Enpp-1-IN-27 can used for the studies of breast cancer and colon cancer[1].
Molecular Weight:
374.85
CAS Number:
[3105103-33-8]
Formula:
C13H19ClN6O3S
Target:
Phosphodiesterase (PDE),STING
Application Notes:
MCE Product type: Reference compound
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