ClpP modulator-1 (Compound BC8a), a peptidomimetic, is an allosteric ClpP modulator. ClpP modulator-1 is a ClpP activator at low concentration with EC50s of 0.35 and 0.58 µM for for Neisseria meningitides ClpP (NmClpP) and Escherichia coli ClpP (EcClpP), resepectively. ClpP modulator-1 also inhibits peptidase activity at high concentration by competitively inhibiting substrate protein (LY-AMC) binding to ClpP C sites. ClpP modulator-1 has antibacterial activity. ClpP modulator-1 can be used for bacterial infections research[1].
Molekulargewicht:
412.72
CAS Nummer:
[2363753-48-2]
Formel:
C19H30BClN2O5
Target-Kategorie:
ClpP
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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