RSL3-NH2 is a GPX4 inhibitor and ferroptosis (ferroptosis) inducer. RSL3-NH2 triggers the iron-dependent cell death pathway associated with lipid peroxidation by inhibiting GPX4 activity. RSL3-NH2 exhibits significant cytotoxicity against colorectal cancer cells and effectively induces their ferroptosis. RSL3-NH2 can serve as a ADC payload for synthesizing antibody-drug conjugates (ADC) and be used in colorectal cancer-related research[1].
Molekulargewicht:
397.85
CAS Nummer:
[3051815-39-2]
Formel:
C21H20ClN3O3
Target-Kategorie:
ADC Payload,Ferroptosis,Glutathione Peroxidase
Anwendungsbeschreibung:
MCE Product type: Reference compound1
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
