BChE/p38-alpha MAPK-IN-1, CAS [[3077831-11-6]] Preis auf Anfrage

Produktübersicht

• Artikelname: BChE/p38-alpha MAPK-IN-1, CAS [[3077831-11-6]] Preis auf Anfrage
• Artikelnummer: MCE-HY-175655
• Hersteller Artikelnummer: HY-175655
• Alternativnummer: MCE-HY-175655-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

BChE/p38-alpha MAPK-IN-1 is a selective dual inhibitor of hBChE (IC50 = 772 nM) and p38alpha MAPK (IC50 = 191 nM). BChE/p38-alpha MAPK-IN-1 reduces the production of pro-inflammatory cytokines (IL-1beta, IL-6, IL-8, TNF-alpha) in cells. BChE/p38-alpha MAPK-IN-1 improves Scopolamine (HY-N0296)-induced cognitive impairment, as well as alleviates LPS (HY-D1056)-induced spatial learning impairment and exerts anti-neuroinflammatory effects in mice. BChE/p38-alpha MAPK-IN-1 can be used for the study of Alzheimers disease (AD) by targeting both cholinergic deficit and neuroinflammation[1].

Produkteigenschaften

• Molekulargewicht: 454.56
• CAS Nummer: [3077831-11-6]
• Formel: C26H32F2N4O
• Target-Kategorie: Cholinesterase (ChE),Interleukin Related,p38 MAPK

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound1