BChE/p38-alpha MAPK-IN-1, CAS [[3077831-11-6]] Preis auf Anfrage

Catalog Number: MCE-HY-175655
Article Name: BChE/p38-alpha MAPK-IN-1, CAS [[3077831-11-6]] Preis auf Anfrage
Biozol Catalog Number: MCE-HY-175655
Supplier Catalog Number: HY-175655
Alternative Catalog Number: MCE-HY-175655-1UNIT
Manufacturer: MedchemExpress
Category: Biochemikalien
BChE/p38-alpha MAPK-IN-1 is a selective dual inhibitor of hBChE (IC50 = 772 nM) and p38alpha MAPK (IC50 = 191 nM). BChE/p38-alpha MAPK-IN-1 reduces the production of pro-inflammatory cytokines (IL-1beta, IL-6, IL-8, TNF-alpha) in cells. BChE/p38-alpha MAPK-IN-1 improves Scopolamine (HY-N0296)-induced cognitive impairment, as well as alleviates LPS (HY-D1056)-induced spatial learning impairment and exerts anti-neuroinflammatory effects in mice. BChE/p38-alpha MAPK-IN-1 can be used for the study of Alzheimers disease (AD) by targeting both cholinergic deficit and neuroinflammation[1].
Molecular Weight: 454.56
CAS Number: [3077831-11-6]
Formula: C26H32F2N4O
Target: Cholinesterase (ChE),Interleukin Related,p38 MAPK
Application Notes: MCE Product type: Reference compound1