CT-996 is an orally active GLP-1RA agonist, with an EC50 of 0.49 nM. CT-996 reduces the beta-arrestin recruitment and GLP-1R internalization. CT-996 suppresses postprandial blood glucose following a mixed meal tolerance test (MMTT) in mice expressing the human GLP-1 receptor and enhances glucose stimulated insulin secretion (GSIS) during an intravenous glucose challenge in obese monkeys. CT-996 can be used for the study of type 2 diabetes (T2D) and obesity[1][2].
Molekulargewicht:
579.59
Reinheit:
99.97
CAS Nummer:
[2810808-95-6]
Formel:
C30H31F2N5O5
Target-Kategorie:
Arrestin,GLP Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
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