CT-996 is an orally active GLP-1RA agonist with an EC50 of 0.49 nM. CT-996 reduces the recruitment of beta-arrestin and the internalization of GLP-1R. CT-996 suppresses postprandial blood glucose in mice expressing human GLP-1 receptors and enhances glucose-stimulated insulin secretion (GSIS) in obese monkeys during intravenous glucose challenge. CT-996 can be used for the research of type 2 diabetes (T2D) and obesity[1][2].
Molecular Weight:
579.59
Purity:
99.97
CAS Number:
[2810808-95-6]
Formula:
C30H31F2N5O5
Target:
Arrestin,GLP Receptor
Application Notes:
MCE Product type: Reference compound
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