AChE-IN-94 is an orally active and blood-brain barrier penetrable AChE inhibitor with an IC50 of 0.40 µM and Ki of 0.28 µM. AChE-IN-94 prevents self-induced and AChE-mediated Abeta1-42 aggregation. AChE-IN-94 alleviates cognitive/memory deficits in Scopolamine (HY-N0296)-induced amnesic model. AChE-IN-94 can be used for the study of Alzheimers disease (AD)[1].
Molekulargewicht:
432.90
Formel:
C20H18ClFN4O2S
Target-Kategorie:
Amyloid-beta,Cholinesterase (ChE)
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
