HBI-2375, CAS [[2982574-79-6]]

Produktübersicht

• Artikelname: HBI-2375, CAS [[2982574-79-6]]
• Artikelnummer: MCE-HY-175802
• Hersteller Artikelnummer: HY-175802
• Alternativnummer: MCE-HY-175802-25MG,MCE-HY-175802-10MG,MCE-HY-175802-1MG,MCE-HY-175802-5MG,MCE-HY-175802-50MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: HYBI-084

Produktbeschreibung

HBI-2375 (HYBI-084) is a brain-penetrant WDR5 inhibitor with an IC50 of 4.48 nM. HBI-2375 binds to the WINR5 and disrupts MLL1-WDR5 protein-protein interactions. HBI-2375 inhibits cancer cells proliferation and shows anti-tumor activity in AML mouse models, and increases tumor CD8+ cytotoxic T lymphocyte infiltration. HBI-2375 inhibits hERG with an IC50 of 17 µM[1][2].

Produkteigenschaften

• Molekulargewicht: 616.11
• Reinheit: 98.06
• CAS Nummer: [2982574-79-6]
• Formel: C29H36ClF2N9O2
• Target-Kategorie: Potassium Channel,WDR5

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound