HBI-2375, CAS [[2982574-79-6]]

Product Overview

• Article Name: HBI-2375, CAS [[2982574-79-6]]
• Biozol Catalog Number: MCE-HY-175802
• Supplier Catalog Number: HY-175802
• Alternative Catalog Number: MCE-HY-175802-25MG,MCE-HY-175802-10MG,MCE-HY-175802-1MG,MCE-HY-175802-5MG,MCE-HY-175802-50MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: HYBI-084

Product Description

HBI-2375 (HYBI-084) is a brain-penetrant WDR5 inhibitor with an IC50 of 4.48 nM. HBI-2375 binds to the WINR5 and disrupts MLL1-WDR5 protein-protein interactions. HBI-2375 inhibits cancer cells proliferation and shows anti-tumor activity in AML mouse models, and increases tumor CD8+ cytotoxic T lymphocyte infiltration. HBI-2375 inhibits hERG with an IC50 of 17 µM[1][2].

Product Properties

• Molecular Weight: 616.11
• Purity: 98.06
• CAS Number: [2982574-79-6]
• Formula: C29H36ClF2N9O2
• Target: Potassium Channel,WDR5

Application Notes

• Application Notes: MCE Product type: Reference compound