MU876 (Compound 32) is a MUS81 inhibitor with an IC50 of 0.5 µM. MU876 effectively inhibits MUS81-dependent homologous recombination (HR) and break-induced replication (BIR) pathways. MU876 sensitizes cancer cells to DNA-damaging agents, such as Cisplatin (HY-17394), through impairing their ability to repair DNA lesions. MU876 can be used for cancers chemotherapy research[1].
Molekulargewicht:
438.44
CAS Nummer:
[208829-24-6]
Formel:
C24H18N6O3
Target-Kategorie:
Endonuclease
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
