Tau Protein Phosphorylation-IN-1, CAS [[3075165-36-2]] Preis auf Anfrage

Produktübersicht

• Artikelname: Tau Protein Phosphorylation-IN-1, CAS [[3075165-36-2]] Preis auf Anfrage
• Artikelnummer: MCE-HY-175841
• Hersteller Artikelnummer: HY-175841
• Alternativnummer: MCE-HY-175841-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

Tau Protein Phosphorylation-IN-1 is a tau protein phosphorylation inhibitor that potently protects PC12 cells against Abeta25-35-induced cytotoxicity (EC50 = 1.93 µM), and can penetrate the blood-brain barrier (BBB).Tau Protein Phosphorylation-IN-1 reverses the hyperphosphorylation of tau, significantly inhibits the expression of certain immune-related cytotoxic factors, suppresses the MAPK and NF-kappaB signaling pathways, and significantly inhibits the expression of RAGE and the apoptosis factors Bax/Bcl-2, both in vitro and in vivo. Tau Protein Phosphorylation-IN-1 relieves nerve damage, and improves learning and memory in an Alzheimers disease (AD) mouse model. Tau Protein Phosphorylation-IN-1 can be used for AD research[1].

Produkteigenschaften

• Molekulargewicht: 628.89
• CAS Nummer: [3075165-36-2]
• Formel: C39H56N4O3
• Target-Kategorie: Apoptosis,Bcl-2 Family,ERK,JNK,NF-kappaB,p38 MAPK,Tau Protein

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound