Tau Protein Phosphorylation-IN-1, CAS [[3075165-36-2]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-175841
Supplier Catalog Number:
HY-175841
Alternative Catalog Number:
MCE-HY-175841-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Tau Protein Phosphorylation-IN-1 is a tau protein phosphorylation inhibitor that potently protects PC12 cells against Abeta25-35-induced cytotoxicity (EC50 = 1.93 µM), and can penetrate the blood-brain barrier (BBB).Tau Protein Phosphorylation-IN-1 reverses the hyperphosphorylation of tau, significantly inhibits the expression of certain immune-related cytotoxic factors, suppresses the MAPK and NF-kappaB signaling pathways, and significantly inhibits the expression of RAGE and the apoptosis factors Bax/Bcl-2, both in vitro and in vivo. Tau Protein Phosphorylation-IN-1 relieves nerve damage, and improves learning and memory in an Alzheimers disease (AD) mouse model. Tau Protein Phosphorylation-IN-1 can be used for AD research[1].
Molecular Weight:
628.89
CAS Number:
[3075165-36-2]
Formula:
C39H56N4O3
Target:
Apoptosis,Bcl-2 Family,ERK,JNK,NF-kappaB,p38 MAPK,Tau Protein
Application Notes:
MCE Product type: Reference compound
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