AChE/BChE-IN-30 (Compound 3g) is a Cholinesterase dual-target competitive inhibitor. AChE/BChE-IN-30 can inhibit AChE and BChE with IC50 values of 0.338 and 2.087 µM and Ki values of 0.045 and 0.789 µM. AChE/BChE-IN-30 has no obvious toxicity to human umbilical vein endothelial cells (HUVEC) and does not inhibit the CYP2C19 enzyme. AChE/BChE-IN-30 can be used for the research of neurological disease, such as Alzheimers disease[1].
Molekulargewicht:
486.61
Formel:
C26H22N4O2S2
Target-Kategorie:
Cholinesterase (ChE)
Anwendungsbeschreibung:
MCE Product type: Reference compound1
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
