AChE/BChE-IN-30 (Compound 3g) is a Cholinesterase dual-target competitive inhibitor. AChE/BChE-IN-30 can inhibit AChE and BChE with IC50 values of 0.338 and 2.087 µM and Ki values of 0.045 and 0.789 µM. AChE/BChE-IN-30 has no obvious toxicity to human umbilical vein endothelial cells (HUVEC) and does not inhibit the CYP2C19 enzyme. AChE/BChE-IN-30 can be used for the research of neurological disease, such as Alzheimers disease[1].
Molecular Weight:
486.61
Formula:
C26H22N4O2S2
Target:
Cholinesterase (ChE)
Application Notes:
MCE Product type: Reference compound1
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