BP-198 is an Mpro PROTAC degrader. BP-198 promotes the ubiquitination and degradation of Mpro. BP-198 has antiviral effects against SARS-CoV-2 (IC50: 11.8 µM) and has stronger activity against drug-resistant viruses. (Pink: target protein ligand (HY-176442), blue: E3 ligase ligand (HY-176441), black: linker (HY-W457968), E3 ligase-linker conjugate (HY-176443))[1].
Molekulargewicht:
1251.37
Formel:
C56H72F6N12O10S2
Target-Kategorie:
PROTACs,SARS-CoV,Virus Protease
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten