CDK2 degrader 6, CAS [[3036606-92-2]]

Produktübersicht

• Artikelname: CDK2 degrader 6, CAS [[3036606-92-2]]
• Artikelnummer: MCE-HY-176444
• Hersteller Artikelnummer: HY-176444
• Alternativnummer: MCE-HY-176444-5MG,MCE-HY-176444-10MG,MCE-HY-176444-1MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

CDK2 degrader 6 is an orally active and potent CDK2 molecular glue degrader with a DC50 of 46.5 nM. CDK2 degrader 6 binds to cereblon and CDK2 to induce ubiquitination and subsequent proteasomal degradation of CDK2. CDK2 degrader 6 modulates cell cycle in breast cancer cells. CDK2 degrader 6 reduces proliferation of breast cancer cells. CDK2 degrader 6 exhibits in vivo antitumor activity in gastric cancer mouse models. CDK2 degrader 6 can be used for the research of breast cancer, gastric cancer[1].

Produkteigenschaften

• Molekulargewicht: 511.44
• Reinheit: 99.81
• CAS Nummer: [3036606-92-2]
• Formel: C23H22F5N5O3
• Target-Kategorie: CDK,Molecular Glues

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound