CDK2 degrader 6, CAS [[3036606-92-2]]

Product Overview

• Article Name: CDK2 degrader 6, CAS [[3036606-92-2]]
• Biozol Catalog Number: MCE-HY-176444
• Supplier Catalog Number: HY-176444
• Alternative Catalog Number: MCE-HY-176444-5MG,MCE-HY-176444-10MG,MCE-HY-176444-1MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

CDK2 degrader 6 is an orally active and potent CDK2 molecular glue degrader with a DC50 of 46.5 nM. CDK2 degrader 6 binds to cereblon and CDK2 to induce ubiquitination and subsequent proteasomal degradation of CDK2. CDK2 degrader 6 modulates cell cycle in breast cancer cells. CDK2 degrader 6 reduces proliferation of breast cancer cells. CDK2 degrader 6 exhibits in vivo antitumor activity in gastric cancer mouse models. CDK2 degrader 6 can be used for the research of breast cancer, gastric cancer[1].

Product Properties

• Molecular Weight: 511.44
• Purity: 99.81
• CAS Number: [3036606-92-2]
• Formula: C23H22F5N5O3
• Target: CDK,Molecular Glues

Application Notes

• Application Notes: MCE Product type: Reference compound