MBL-II-141, CAS [[1353747-12-2]] Preis auf Anfrage

Produktübersicht

• Artikelname: MBL-II-141, CAS [[1353747-12-2]] Preis auf Anfrage
• Artikelnummer: MCE-HY-17648
• Hersteller Artikelnummer: HY-17648
• Alternativnummer: MCE-HY-17648-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

MBL-II-141 is potent ABCG2 inhibitor with an IC50 of 0.11 µM. MBL-II-141 inhibits the transport function of ABCG2 in a non-competitive manner, preventing ABCG2 from pumping substrates (such as Irinotecan (HY-16562)) out of the cells, thereby increasing the accumulation of drugs within the cells. MBL-II-141 has no effect on ABCB1 (P-gp) and ABCC1 (MRP1) and has extremely low cytotoxicity (IG50 > 100 µM). MBL-II-141 can be used for the study of multidrug resistance (MDR) cancers[1][2].

Produkteigenschaften

• Molekulargewicht: 547.40
• CAS Nummer: [1353747-12-2]
• Formel: C28H23BrN2O5
• Target-Kategorie: BCRP

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound