PRMT5-MTA-IN-4, CAS [[3025838-18-7]] Preis auf Anfrage

Produktübersicht

• Artikelname: PRMT5-MTA-IN-4, CAS [[3025838-18-7]] Preis auf Anfrage
• Artikelnummer: MCE-HY-176701
• Hersteller Artikelnummer: HY-176701
• Alternativnummer: MCE-HY-176701-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

PRMT5-MTA-IN-4 (Compound 30) is a potent irreversible protein arginine methyltransferase 5 (PRMT5) inhibitor (IC50=8 nM). PRMT5-MTA-IN-4 blocks arginine methylation, inhibiting ribosomal RNA processing and cell cycle-related protein expression. PRMT5-MTA-IN-4 exhibits antiproliferative activity in multiple tumor cell lines (e.g., IC50=0.3 µM in DLD-1 cells). PRMT5-MTA-IN-4 is promising for research of hematological malignancies, such as acute myeloid leukemia, diffuse large B-cell lymphoma[1].

Produkteigenschaften

• Molekulargewicht: 504.94
• CAS Nummer: [3025838-18-7]
• Formel: C26H22ClFN6O2
• Target-Kategorie: Histone Methyltransferase

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound